About
Sam J. Louis is a Houston litigation attorney with more than 32 years of experience in white collar defense, government investigations, and healthcare regulatory matters. A former federal prosecutor, he advises corporate entities, executives, and employees facing grand jury investigations, criminal trials, regulatory enforcement proceedings, and federal prosecutions. His practice also covers internal investigations, Foreign Corrupt Practices Act matters, and compliance with federal laws governing food and drug distribution.
Louis earned his Juris Doctor, cum laude, from Texas Southern University’s Thurgood Marshall School of Law, where he participated in the Thurgood Marshall Law Review. He received a Bachelor of Business Administration from Lamar University. His education, combined with decades of courtroom and government experience, provides a strong foundation for analyzing complex evidence, regulatory requirements, and litigation risks.
Before entering private practice, Louis served as deputy criminal chief of the Program Fraud Group for the U.S. Department of Justice in the Southern District of Texas. He supervised 11 attorneys, led more than 200 criminal jury trials, and spent over 10 years as healthcare fraud coordinator. He also directed healthcare fraud and global anti-counterfeiting task forces. His defense work has included healthcare fraud, False Claims Act inquiries, FDA investigations, FCPA matters, financial fraud, and intellectual property crimes.
Sam J. Louis has been recognized by Chambers USA for white collar crime and government investigations, The Best Lawyers in America for white collar criminal defense and health care law, and Texas Super Lawyers. His professional record includes groundbreaking anti-counterfeiting work as the first prosecutor to secure the extradition and prosecution of a foreign national for intellectual property crimes. He also serves the profession and community through advisory, selection-panel, and nonprofit board roles.
Law Office Affiliations
- Partner, Holland & Knight LLP
- Fellow, Texas Bar Foundation, 2017
- Member, National Association of Criminal Defense Lawyers, 2016
- Member, National Trial Lawyers, 2015
- Member, National Bar Association, Commercial Law Section
Licensed State
- Texas
Education
- Texas Southern University, Thurgood Marshall School of Law
Juris Doctor (JD) - Lamar University
Bachelor of Business Administration (BBA)




- Litigation
- White Collar Crime





